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As described by Olagnier et al., an interesting relationship between metabolic reprogramming and antiviral cytosolic DNA sensing in human cells involves Nrf2 [150]

Additionally, upregulated Ras-RAF-MEK pathway expression may enhance cancer cell sensitivity to ferroptosis by modulating VDAC2/3 function and increasing ROS generation (40)

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Puerarin induces Nrf2 as a cytoprotective mechanism to prevent cadmiuminduced autophagy inhibition and NLRP3 inflammasome activation in AML12 hepatic cells

Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors

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